2025
20. Activity-Based Tracking of Glycan Turnover in Microbiomes.
Crawford, C. J.; Reintjes, G.; Solanki, V.; Ricardo, M. G.; Harder, J.; Amann, R.; Hehemann, J.-H.; Seeberger, P. H.*
J. Am. Chem. Soc. 2025, 147, 29, 25799-25805
19. Arylsulfamates Inhibit Colonic Bacteroidota Growth through a Sulfatase-Independent Mechanism.
Crawford, C. J.‡; Tomlinson, C. W. E.‡; Gunawan, C.; Chen, Z.; Byrne, D. P.; Darby, C.; Luis, A. S. J.; Elli, S.; Yates, E. A.; Bolam, D. N.; Post, S. van der; Williams, S. J.*; Cartmell, A.*
Proc. Natl. Acad. Sci. U.S.A. 2025, 122 (28), e2414331122
18. De novo Glycan Annotation of Mass Spectrometry Data.
Bligh, M.*; Silva-Solar, S.; Biehler, L.; Fitzgerald, C. C. J.; Crawford, C. J.; Schultz-Johansen, M.; Niggemeier, S.; Seeberger, P. H.; Liebeke, M.; Hehemann, J.-H.
J. Am. Soc. Mass Spectrom. 2025, 36, 8, 1686-1695
2024
17. Automated Synthesis of Algal Fucoidan Oligosaccharides.
Crawford, C. J.; Schultz-Johansen, M.; Luong, P.; Vidal Melgosa, S.; Hehemann, J.-H.; Seeberger, P. H.*
J. Am. Chem. Soc. 2024, 146 (23), 14715-14726.
16. Synthetic Glycans Reveal Determinants of Antibody Functional Efficacy against a Fungal Pathogen.
Crawford, C. J.; Guazzelli, L.‡; McConnell, S. A.‡; McCabe, O.; d'Errico, C.; Greengo, S. D.; Wear, M. P.; Jedlicka, A. E.; Casadevall, A.*; Oscarson, S.*
ACS Infect. Dis. 2024, 10 (2), 475-488.
15. The Structure of a C. neoformans Polysaccharide Motif Recognized by Protective Antibodies: A Combined NMR and MD Study.
Hargett, A. A.‡; Azurmendi, H. F.‡; Crawford, C. J.; Wear, M. P.; Oscarson, S.; Casadevall, A.*; Freedberg, D. I.*
Proc. Natl. Acad. Sci. U.S.A. 2024, 121 (7), e2315733121.
14. Semisynthetic Glycoconjugate Vaccine Candidate against Cryptococcus neoformans.
Crawford, C. J.; Liporagi-Lopes, L.; Coelho, C.; Junior, S. R. S.; Nicola, A. M.; Wear, M. P.; Vij, R.; Oscarson, S.*; Casadevall, A.*
ACS Infect. Dis. 2024, 10, 6, 2089–2100
2023
13. Advances in Glycoside and Oligosaccharide Synthesis.
Crawford, C. J.; Seeberger, P. H.*
Chem. Soc. Rev. 2023, 52 (22), 7773–7801.
12. Synthesis of Glycosides.
Crawford, C. J.*; Seeberger, P. H.*
Comprehensive Organic Synthesis (Third Edition) 2023, 6, 433-450
2022
11. Glycoside Hydrolase from the GH76 Family Indicates That Marine Salegentibacter sp. Hel_I_6 Consumes α-Mannan from Fungi.
Solanki, V.; Krüger, K.; Crawford, C. J.; Pardo-Vargas, A.; Danglad-Flores, J.; Hoang, K. L. M.; Klassen, L.; Abbott, D. W.; Seeberger, P. H.; Amann, R. I.; Teeling, H.*; Hehemann, J.-H.*
ISME J 2022, 16 (7), 1818–1830.
10. Lyophilization Induces Physicochemical Alterations in Cryptococcal Exopolysaccharide.
Wear, M. P.*; Hargett, A. A.; Kelly, J. E.; McConnell, S. A.; Crawford, C. J.; Freedberg, D. I.; Stark, R. E.; Casadevall, A.
Carbohydr. Polym. 2022, 291, 119547.
9. Cryptococcus neoformans Capsule Regrowth Experiments Reveal Dynamics of Enlargement and Architecture.
Wear, M. P.; Jacobs, E.; Wang, S.; McConnell, S. A.; Bowen, A.; Strother, C.; Cordero, R. J. B.; Crawford, C. J.; Casadevall, A.
J. Biol. Chem. 2022, 298 (4), 101769.
2021
8. Optimized Henry Reaction Conditions for the Synthesis of an L-Fucose C-Glycosyl Derivative.
Hauck, D.; Jumde, V. R.; Crawford, C. J.; Titz, A.*
Carbohydr. Chem. 2021, 17–22.
7. A Glycan FRET Assay for Detection and Characterization of Catalytic Antibodies to the Cryptococcus neoformans Capsule.
Crawford, C. J.; Wear, M. P.; Smith, D. F. Q.; D'Errico, C.; McConnell, S. A.; Casadevall, A.*; Oscarson, S.*
Proc. Natl. Acad. Sci. U.S.A. 2021, 118 (5), e2016198118.
6. Defining the Qualities of High-Quality Palladium on Carbon Catalysts for Hydrogenolysis.
Crawford, C. J.*; Qiao, Y.; Liu, Y.; Huang, D.; Yan, W.; Seeberger, P. H.; Oscarson, S.*; Chen, S.*
Org. Process Res. Dev. 2021, 25 (7), 1573–1578.
2020
5. Optimized Conditions for the Palladium-Catalyzed Hydrogenolysis of Benzyl and Naphthylmethyl Ethers: Preventing Saturation of Aromatic Protecting Groups.
Crawford, C.; Oscarson, S.*
Eur. J. Org. Chem. 2020, 3332–3337.
4. A Synthetic Glycan Array Containing Cryptococcus neoformans Glucuronoxylomannan Capsular Polysaccharide Fragments Allows the Mapping of Protective Epitopes.
Guazzelli, L.; Crawford, C. J.; Ulc, R.; Bowen, A.; McCabe, O.; Jedlicka, A. J.; Wear, M. P.; Casadevall, A.*; Oscarson, S.*
Chem. Sci. 2020, 11 (34), 9209–9217.
3. Convergent Total Synthesis of Cryptococcus neoformans Serotype B Capsule Repeating Motif.
Crawford, C. J.*; Oscarson, S.
Carbohydr. Res. 2020, 497, 108150.
2. Variation in Cell Surface Hydrophobicity among Cryptococcus neoformans Strains Influences Interactions with Amoebas.
Vij, R.; Danchik, C.; Crawford, C.; Dragotakes, Q.; Casadevall, A.*
mSphere 2020, 5 (2).
1. Exploring Cryptococcus neoformans Capsule Structure and Assembly with a Hydroxylamine-Armed Fluorescent Probe.
Crawford, C. J.; Cordero, R. J. B.; Guazzelli, L.; Wear, M. P.; Bowen, A.; Oscarson, S.*; Casadevall, A.*
J. Biol. Chem. 2020, 295 (13), 4327–4340.